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Buy Melanotan I Peptide

Melanotan I is a synthetic peptide designed to stimulate skin pigmentation by increasing melanin production in the body. It is commonly used to achieve a tanned appearance without excessive sun exposure, offering potential benefits in reducing UV-related skin damage. Additionally, research suggests it may have therapeutic applications for conditions like vitiligo by promoting even skin tone and pigmentation.

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Melanotan I Peptide Products

PharmaGrade.Store supplies a number of Melanotan I Netherlands peptide products for clinical research use:

    • Melanotan I Peptide Vial – A sterile, glass vial containing lyophilized Melanotan I, ready for reconstitution using bacteriostatic water.
      Melanotan I is available in 10 mg peptide vials.
    • Melanotan I Nasal Spray – A pre-mixed, ready to use Melanotan I solution. Choose from 15ml or 30ml Melanotan 1 nasal sprays here.
    • Melanotan I Pre-Mixed Peptide Pen – Pre-mixed peptide pen kits, and cartridges come ready reconstituted with bacteriostatic water. Available in 10mg peptide pen kits.

Melanotan I Mechanism of Action

Melanotan I is a synthetic peptide primarily designed to enhance skin pigmentation by mimicking the effects of the natural hormone alpha-melanocyte-stimulating hormone (α-MSH). It acts on melanocortin receptors, particularly MC1R, found on melanocytes, the cells responsible for producing melanin [1]. This activation increases melanin synthesis, resulting in a tanned appearance without needing prolonged sun exposure [2].

Melanotan I offers potential benefits in reducing UV-associated skin damage and has been studied as a therapeutic option for conditions like vitiligo, as it promotes even pigmentation [3]. Its ability to provide controlled skin tanning has also made it a subject of interest in cosmetic and medical applications.

Melanotan I Peptide Benefits

Netherlands Laboratory studies and in vitro testing have demonstrated that BPC-157 peptide could hold the following benefits:

  • Sunless Tanning: Melanotan I enhances skin pigmentation by stimulating melanin production in melanocytes. This minimizes the risk of UV-related skin damage, including sunburn and skin cancer [4].
  • Potential treatment for skin conditions: Offers potential therapeutic benefits for skin conditions like vitiligo, promoting even pigmentation [3].

Research on Melanotan I Netherlands

Melanotan I has been extensively studied for its ability to enhance skin pigmentation by stimulating melanocortin receptors, specifically MC1R, on melanocytes. Netherlands Research confirms its effectiveness in increasing melanin production, offering a safer alternative to prolonged UV exposure [1].

Clinical trials have explored its potential therapeutic uses, particularly in treating vitiligo and other pigmentation disorders by promoting even skin tone [3]. Netherlands Studies have highlighted its efficacy in reducing risks of UV-related skin damage and its role in cosmetic applications for non-invasive tanning.

While generally well-tolerated, research has also addressed safety concerns, focusing on appropriate dosing to mitigate risks and ensure effective outcomes [5].

Melanotan I Specifications:

View PharmaGrade Store Netherlands Melanotan I HPLC Certificate here.

Amino Acid Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

Molecular Formula: C78H111N21O19

Molecular Weight: 1646.8 g/mol

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Melanotan I & Melanotan II Peptide Stack

Combining Melanotan I and Melanotan II peptides may amplify skin pigmentation benefits and enhance tanning efficiency through synergistic effects on melanin production. Melanotan I focuses on steady, controlled pigmentation, while Melanotan II adds a more potent effect, potentially resulting in quicker and deeper tanning results.

This combination could reduce the need for prolonged sun exposure, minimizing UV-related risks. Additionally, their combined use shows promise in therapeutic studies, particularly in addressing pigmentation disorders like vitiligo, offering a balanced approach to even skin tone and effective tanning solutions.

Buy Melanotan I & Melanotan II Peptide Stack here.

Melanotan 1 or Melanotan 2

Frequently Asked Questions about Melanotan I Netherlands

What is a Melanocortin?

Melanocortins are a group of peptide hormones derived from the proopiomelanocortin (POMC) precursor protein. They include several important hormones such as adrenocorticotropic hormone (ACTH) and the melanocyte-stimulating hormones (MSH). These peptides play crucial roles in various physiological functions, including:

  1. Pigmentation: Melanocortins like α-MSH stimulate the production and release of melanin in skin and hair, affecting pigmentation.

  2. Energy Homeostasis: They are involved in regulating appetite and energy expenditure, influencing body weight and metabolism.

  3. Inflammation and Immune Response: Melanocortins have anti-inflammatory effects and can modulate immune system activity.

  4. Adrenal Function: ACTH, a type of melanocortin, stimulates the adrenal glands to produce cortisol, a hormone important for stress response and metabolism.

These melanocortin type hormones exert their effects by binding to melanocortin receptors, which are distributed throughout the body and are involved in diverse biological processes.

Is Melanotan I approved for human use?

Melanotan I is not approved by the FDA for human use.  PharmaGrade.Store supplies Melanotan I for clinical research use only.

Further Reading

Blogs:

Explore the science and application of tanning peptides, particularly Melanotan I and II. It explains how these peptides stimulate melanin production, offering a sunless tanning solution. The guide discusses the differences between the peptides, their effects, and potential side effects, such as appetite suppression and increased libido. It emphasizes the importance of safe usage, consulting healthcare providers, and understanding the legal status of these peptides, as they are not fully approved for use in many countries.

This blog explores the distinctions between these two tanning peptides. It highlights Melanotan 1’s targeted action on melanocortin 1 receptors, leading to fewer side effects and its regulatory approval for certain medical conditions. In contrast, Melanotan 2 is noted for its broader effects, including increased potency, appetite suppression, and libido enhancement, but with a wider range of side effects. It emphasizes the importance of understanding these differences for safe use, given the unregulated market and potential health risks associated with these peptides. 

Discover the differences between Melanotan I & Melanotan II

Scientific Research:

[1] Mun Y, Kim W, Shin D. Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects. Int J Mol Sci. 2023 Jul 29;24(15):12152.

[2] Dorr RT, Ertl G, Levine N, Brooks C, Bangert JL, Powell MB, Humphrey S, Alberts DS. Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Arch Dermatol. 2004 Jul;140(7):827-35. 

[3] Bellei B, Papaccio F, Picardo M. Regenerative Medicine-Based Treatment for Vitiligo: An Overview. Biomedicines. 2022 Oct 28;10(11):2744.

[4] Stratton SP, Stratton MS, Alberts DS. Promising agents for chemoprevention of skin cancer. Curr Oncol. 2006 Oct;13(5):185-6. 

[5] Langan EA, Nie Z, Rhodes LE. Melanotropic peptides: more than just ‘Barbie drugs’ and ‘sun-tan jabs’? Br J Dermatol. 2010 Sep;163(3):451-5.

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DISCLAIMER: All products sold by PharmaGrade.Store are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals