Buy MGF Peptide

MGF peptide, or Mechano Growth Factor, is a splice variant of the IGF-1 gene, activated in response to muscle damage or mechanical stress. It plays a key role in muscle growth and repair by stimulating satellite cell activation and protein synthesis. This peptide is often explored for its potential beneficial effects to enhance recovery and promote muscle hypertrophy.

Twin Pack Saver

MGF Pre-Mixed Pen 2mg
£23.86 – £64.42 Select options This product has multiple variants. The options may be chosen on the product page
MGF Peptide Vial 2mg
£17.68 – £26.66 Select options This product has multiple variants. The options may be chosen on the product page
MGF Nasal Spray
£25.68 – £46.36 Select options This product has multiple variants. The options may be chosen on the product page

MGF Peptide Products

MGF Peptide is available from PharmaGrade.Store in the following products:

MGF Peptide Vial – MGF peptide, lyophilized, supplied in a sterile, glass vial for intramuscular injection into the subjects of studies. Please note you also require bacteriostatic water to reconstitute the MGF.
MGF is available in 2 mg peptide vials here.
MGF Peptide Nasal Spray – a pre-mixed peptide solution ready for administration into the nasal passage. Choose from 15ml or 30ml nasal sprays here.
MGF Pre-Mixed Peptide Pen – MGF Peptide pen kits and refill cartridges come ready to use, reconstituted with Bac water. Buy MGF Peptide 2mg Pre-Mixed Pen here.

Please note: PharmaGrade.Store supplies MGF Peptide Netherlands products for research purposes only.

MGF Peptide Mechanism

MGF peptide, or Mechano Growth Factor, is produced as a splice variant of the IGF-1 gene in response to mechanical stress or muscle damage [1]. When muscle fibers experience strain, MGF expression is upregulated, playing a crucial role in repair and growth. It activates satellite cells, which are dormant muscle stem cells located on the periphery of muscle fibres [2].

Through the activation of pathways such as the PI3K-Akt signalling cascade, these satellite cells proliferate and differentiate, fusing with damaged fibres to promote regeneration [3]. MGF also stimulates protein synthesis and muscle hypertrophy, making it integral to the body’s adaptive response to physical stress.

MGF Peptide Benefits

Through Netherlands scientific studies, clinical researchers have demonstrated that MGF peptide could have the following benefits and applications:

MGF stimulates muscle growth: enhances muscle tissue hypertrophy by activating satellite cells and increasing protein synthesis [4].
Accelerates muscle repair: It aids in the repair of damaged muscle fibres after mechanical stress or injury [5].
Improves recovery times: By promoting faster muscle regeneration and wound repair, it helps reduce downtime between intense workouts or injuries [5].
Applications in muscle wasting diseases: MGF is being studied for its potential in treating muscle-wasting conditions like sarcopenia and muscular dystrophy [6].
Localized effects: MGF is expressed in specific muscles undergoing stress, allowing targeted repair and growth.

Research on MGF Peptide Netherlands

Netherlands Scientific studies on MGF peptide reveal its significant impact in muscle repair, growth, and recovery. Research indicates that MGF, as a splice variant of IGF-1, activates satellite cells and promotes protein synthesis, enhancing muscle hypertrophy and regeneration after damage [4] [5].

Studies also highlight its therapeutic potential in combatting muscle-wasting conditions like muscular dystrophy and sarcopenia [6]. While promising, challenges exist regarding its stability, optimal dosing, and delivery methods.

However, evidence supporting its efficacy in humans is limited, with most findings derived from in vitro or animal studies. Ongoing research aims to clarify its safety, long-term effects, and broader applications in clinical and athletic settings.

MGF Peptide Specifications:

View PharmaGrade Store Netherlands MGF Peptide HPLC Certificate here.

Amino Acid Sequence: Tyr Gln-Pro Pro-Ser Thr-Asn Lys Asn Thr Lys-Ser Gln Arg Arg Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-Cys

Molecular Formula: F3Mg

Molecular Weight: 81.3 g/mol

Buy MGF Peptide Netherlands for research use online from PharmaGrade.Store today!

Frequently Asked Questions about MGF Peptide Netherlands

What is the difference between MGF and PEG-MGF peptides?

Difference Between MGF and PEG-MGF Peptides

Structure: MGF (Mechano Growth Factor) is a natural splice variant of IGF-1, expressed in response to muscle damage. PEG MGF is a modified version of MGF where a polyethylene glycol (PEG) group is attached to improve its properties.
Stability: MGF has a short half-life, making it less stable and quickly broken down in the body. PEGylation increases stability by shielding the peptide from enzymatic degradation.
Half-Life and Bioavailability: MGF has a very short half-life of just minutes, whereas PEG-MGF boasts a prolonged half-life, potentially lasting hours, allowing for improved bioavailability and systemic effects.
Function: Both peptides promote muscle repair and growth by activating satellite cells and protein synthesis. PEG-MGF’s longer half-life enables it to circulate systemically, targeting more muscles, while MGF works mainly at the localized site of expression.
Applications:
- MGF: Ideal for targeted repair but limited by its rapid breakdown.
- PEG-MGF: Superior for systemic muscle recovery and broader therapeutic potential due to extended activity.

Each peptide’s usage depends on specific goals like localized treatment (MGF) or systemic effects (PEG-MGF).

What is the correct way to store MGF Peptide?

MGF peptide is typically delivered in a lyophilized solid form and should be stored in a freezer at or below -20°C for long term storage. Once reconstituted, the peptide solution should be stored at 4°C and used within a short term, usually 24 hours. MGF has not yet been approved for human consumption. MGF is for laboratory purposes only.

Blogs:

Unlocking the Power of MGF Peptide for Muscle Recovery

It highlights MGF as a splice variant of IGF-1, emphasizing its role in activating satellite cells to promote muscle hypertrophy and repair. The article discusses MGF’s unique properties, such as its ability to enhance muscle strength and prevent muscle wasting, making it popular among bodybuilders and athletes. Additionally, it touches on the peptide’s potential therapeutic applications, including its effects on cardiac function and possible benefits for brain health.

Read about Muscle Recovery

A Guide to Tendonitis Treatment and Tissue Repair

This blog discusses the use of peptide therapy for treating tendonitis and aiding tissue repair. The article emphasizes the potential of peptides like BPC-157 and Thymosin Beta 4 in accelerating tissue regeneration, reducing inflammation, and improving recovery outcomes. It also covers the benefits of targeted peptide therapy, which minimizes side effects and maximizes healing potential, making it a promising approach for managing tendonitis and other tissue-related injuries.

Explore the full blog

Scientific Research:

[1] Matheny RW Jr, Nindl BC, Adamo ML. Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration. Endocrinology. 2010 Mar;151(3):865-75.

[2] Yin H, Price F, Rudnicki MA. Satellite cells and the muscle stem cell niche. Physiol Rev. 2013 Jan;93(1):23-67.

[3] Fu X, Wang H, Hu P. Stem cell activation in skeletal muscle regeneration. Cell Mol Life Sci. 2015 May;72(9):1663-77.

[4] Iida K, Itoh E, Kim DS, del Rincon JP, Coschigano KT, Kopchick JJ, Thorner MO. Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice. J Physiol. 2004 Oct 15;560(Pt 2):341-9.

[5] Liu X, Zeng Z, Zhao L, Chen P, Xiao W. Impaired Skeletal Muscle Regeneration Induced by Macrophage Depletion Could Be Partly Ameliorated by MGF Injection. Front Physiol. 2019 May 17;10:601.

[6] Scicchitano BM, Rizzuto E, Musarò A. Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging (Albany NY). 2009 May 13;1(5):451-7.

Buy MGF Peptide Netherlands Today from PharmaGrade.Store

ALL PRODUCT INFORMATION AND ARTICLES ON THIS SITE ARE FOR EDUCATIONAL PURPOSES ONLY

DISCLAIMER: All products sold by PharmaGrade.Store are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals